Working with Humanized NSG mice: In-sourced or Out-sourced

  The term “humanized” mouse can mean many things to many people. Here, we’ll define humanized mice as a mouse that harbors engrafted human tissue or cells, such as immune cells. Whether you...

Modeling a Population: An Overview of JAX Diversity Outbred Mice

Join us today for a conversation on Diversity Outbred Mice with Kelly Brackett, Ph.D. and Elizabeth Axton, Ph.D. -- Want to learn more? Read our latest blog: http://www.jax.org/news-and-insights/2019

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  You may have noticed that the latest biomedical breakthroughs are utilizing more and more humanized mice. But, what is a humanized mouse and why would scientists want to utilize this type of...

MiceTech Talk Episode 12: Let's Talk Latest Advances in Alzheimer's Disease Research (Aug. 4, 2020)

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MiceTech Talk Episode 11: Let's Talk Knockouts (July 28, 2020)

In this episode, we talk about how you can CRISPR your way to a faster, easier mouse knockout model. We also leave you with some tips to consider for generating your very own knockout mouse model!

Tomorrow's Autoimmune Research Today: Mouse Models, Type 1 Diabetes, and More

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Genotyping JAX Mice

This course serves as a helpful resource in your laboratory mouse research.

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Watch this video to learn the process of generating and characterizing “humanized” NSG™ (Hu-NSG™) mice and view data demonstrating preclinical research applications of these novel mouse models.

Generating Better Mouse Models for Your Research: Approaches and Considerations

Check out this video for experience-based insights that can help you make decisions during your model development process.

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JAXLive! A preview of Immunology Scientific Sessions -- CRS, NSG Mice, and More

Join Drs. Kyle Draheim and Dr. Jenny Morgenweck today as they give a preview of our upcoming Immunology scientific sessions on Monday, July 20. Learn More: http://www.jax.org/jax-mice-and-services/in

MiceTech Talk Episode 8: Let's Talk Checklists for a Well-Written Manuscript (June 30, 2020)

What is the key information you need to include in your paper to ensure that your studies meet the highest standards of scientific rigor and transparency? In this episode, we help you with some tips o

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Have you ever looked at a strain name and wondered what all those letters and numbers are and why they are important? Nomenclature can tell you a lot about what the appropriate control mice for your e

MiceTech Talk Episode 6: Let's Talk Breeding (June 16, 2020)

Is breeding mice getting you down? Trying to figure out the best way to maintain your strains? Are your mice going through a breeding slump? Breeding can be challenging but it doesn’t always have to b

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  Under certain circumstances in patients, the human immune system can spin out of control and become highly toxic, resulting in cytokine release syndrome (CRS). CRS has been observed in certain...

MiceTech Talk Episode 10: Let's Talk Humanized Mice Part 2 (July 21, 2020)

CONTINUOUS INNOVATION OF CLINICAL ONCOLOGY DATA WITH CKB

When people think of innovation, often times they think of new products like iPhones and companies like SpaceX. But innovation spans far beyond what one may typically think of and can be applied...

Moving beyond amyloid to treat Alzheimer's disease

Beta-amyloid peptid. The amyloid precursor protein being cleaved by gamma and beta secretases and releasing the amyloid beta peptide, which can accumulate to amyloid plaques, one of the main...

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